17-P038 Sox3 as a transcriptional repressor
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چکیده
منابع مشابه
17-P038 Sox3 as a transcriptional repressor
immediate early step in PrE specification. We show that the fraction cells present with in this state is influenced by factors that both promote and suppress primitive PrE differentiation, however conditions that support ES cell self-renewal prevent their progression into endoderm differentiation and support an equilibrium between this state and at least one other that resembles the inner cell ...
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The yeast protein Xtc1 was identified as a protein that binds directly and specifically to the activation domains of acidic activators such as E2F-1, Gal4 and VP16. Additionally, it was shown to co-purify with the RNA polymerase II holoenzyme complex and it was suggested that Xtc1 functions as a regulator of transcription that modulates the response of RNA polymerase II to transcriptional activ...
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BACKGROUND NRP/B, a family member of the BTB/Kelch repeat proteins, is implicated in neuronal and cancer development, as well as the regulation of oxidative stress responses in breast and brain cancer. Our previous studies indicate that the NRP/B-BTB/POZ domain is involved in the dimerization of NRP/B and in a complex formation with the tumor suppressor, retinoblastoma protein. Although much ev...
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BACKGROUND Although most circadian clock components are conserved between Drosophila and mammals, the roles assigned to the CRYPTOCHROME (CRY) proteins are very different: Drosophila CRY functions as a circadian photoreceptor, whereas mammalian CRY proteins (mCRY1 and 2) are transcriptional repressors essential for molecular clock oscillations. RESULTS Here we demonstrate that Drosophila CRY ...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2009
ISSN: 0925-4773
DOI: 10.1016/j.mod.2009.06.759